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graph pad prizm version 7.04  (GraphPad Software Inc)


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    GraphPad Software Inc graph pad prizm version 7.04
    Graph Pad Prizm Version 7.04, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/graph+pad+prizm+version+7%2E04/graph+pad+prizm+version+7+04/pm37308045-117-8-13
    Average 90 stars, based on 1 article reviews
    graph pad prizm version 7.04 - by Bioz Stars, 2026-11
    90/100 stars

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    Article Title: Evaluation of neurobiological and antioxidant effects of novel melatonin analogs in mice
    Article Snippet: Figures were prepared with box plots Figures, calculations, and statistical analyses were performed with Graph Pad Prizm version 7.04 (GraphPad Software, San Diego, CA, USA) and SigmaStat® 11.0 (Systat Software Inc., San Rose, USA).

    Article Title: Spectral and electrochemical solvatochromic investigations of newly synthesized peptide-based chemosensor bearing azobenzene side chain bio photoswitch
    Article Snippet: In the present study, a novel analogue of azobenzene-containing hemorphin-4 has been synthesized and investigated for assessment of spectral, electrochemical, and biological effects.. The synthesis was achieved by a modified solid-phase peptide synthesis (SPPS) by Fmoc-strategy.. This compound represents a newly synthesized and unstudied peptide-based chemosensor bearing azobenzene side-chain with different spectral and electrochemical properties in the two trans-/cis-states depending on the solvent polarity.

    Article Title: Structure-activity relationship study on new hemorphin-4 analogues containing steric restricted amino acids moiety for evaluation of their anticonvulsant activity.
    Article Snippet: In the present study, several new analogues of hemorphin-4, modified with unnatural conformationally restricted amino acids followed the structure Aaa–Tyr–Xxx–Trp–Thr–NH2, where Aaa is the low-molecular-weight lipophilic adamantyl building block, and Xxx is Ac5c (1-aminocyclopentanecarboxylic acid) or Ac6c (1-aminocyclohexane carboxylic acid) was synthesized, characterized and investigated for anticonvulsant activity in three seizure tests, the maximal electroshock test (MES), 6-Hz psychomotor seizure test and timed intravenous pentylenetetrazole infusion (ivPTZ) test.. The acute neurological toxicity was determined using the rota-rod test.. The new synthetic neuropeptide analogues were prepared by solid-phase peptide synthesis—Fmoc chemistry and were evaluated in three doses of 1, 3 and 5 μg, respectively, administered intracerebroventricularly in male ICR mice.

    Article Title: Spontaneously hypertensive rats vs. Wistar Kyoto and Wistar rats: An assessment of anxiety, motor activity, memory performance, and seizure susceptibility.
    Article Snippet: Figures, calculations, and statistical analyses were performed with Graph Pad Prizm version 7.04 (GraphPad Software, San Diego, CA, USA) and SigmaStat® 11.0 (Systat Software Inc., San Rose, USA).

    Article Title: Lipid nano-carriers loaded with Cannabis sativa extract for epilepsy treatment - in vitro characterization and in vivo efficacy studies.
    Article Snippet: Taking into consideration the latest reported beneficial anticolvusant effects of cannabidiol (CBD) and cannabiodiolic acid (CBDA) for clinical applications and the advantages of lipid nano-systems as carriers for targeted brain delivery, the aim of this study was set in direction of in vitro physico-chemical and biopharmaceutical characterization and in vivo evaluation of nanoliposomes and nanostructured lipid carriers loaded with Cannabis sativa extract intended for safe and efficient transport via blood-brain barrier and treatment of epilepsy.. These nanoliposomes and nanostructured lipid formulations were characterized with z-average diameter <200 nm, following unimodal particle size distribution, negative values for Z-potential, high drug encapsulation efficiency and prolonged release during 24h (38.84-60.91 %).. Prepared formulations showed statistically significant higher antioxidant capacity compared to the extract.

    Article Title: Investigation of the structure-activity relationship in a series of new LVV- and VV-hemorphin-7 analogues designed as potential anticonvulsant agents.
    Article Snippet: In the present study, a series of new analogues of both LVVand VV-hemorphin-7 have been synthesized and characterized.. They were modified at the Nand C-terminus with varied amino acids (Ile, D-Leu, D-Val, D-Phe) and enantiopure chiral Sand Rα-aminophosphonic acids ((dimethoxyphosphoryl)methyl)-valine and ((dimethoxyphosphoryl) methyl)-leucine) to optimize the physicochemical properties and to enhance their anticonvulsant potency.. The novel peptide analogues were prepared by solid-phase peptide synthesis—Fmoc-strategy.



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